The package Moreover, the EbM extract can potentiate the relaxation effects induced by PDE 5 inhibitors such as sildenafil and vardenafil. Clin Chim Acta12:671683, 1965. Recently, many specific PDE 5 inhibitors have been introduced in clinical studies. The organ bath for rabbit CC strips was prepared with some modification as described previously.15In brief, the entire penile tissue was transected from the base, quickly rinsed and kept immersed in oxygenated Krebs' physiological solution at 37C. The order of extracts potency (EPW>EP-20>EP-20-1 to EP-20-6) indicates that the bioactivity is getting lost during the process of purification. HARD STEEL ORIGINAL FORMULATED MALE ENHANCEMENT uses palm oil that already contains significant amounts of saturated fats providing abundant stearic acid. Many effects such as facial flushing, dizziness, blue vision and headache have been described, although the rate of interruption of such treatment is low. Falsepositive CDT results can be found in patients with an inborn error of glycoprotein metabolism or a genetic Dvariant of transferrin. Our study found a twice-daily dose of ginkgo extract help ward off or slow dementia, or memory loss associated with Alzheimers disease in older adults. Zimmermann, H.J., and West, M. Serum enzyme levels in the diagnosis of hepatic disease. Each package has only 1 capsule enclosed in a Whitehead, T.P. These issues have a bearing particularly for new markers for which fully automated test procedures in which we have developed. Data points represent means.e.m. You can tape over the edges or paint them. Use only as directed. It has been reported that nonginkgolide nonflavonoid fraction of ginkgo biloba extract (NGE) has the most potent relaxing effect on vascular smooth muscle. Alcohol AlcoholSuppl 1: 261264, 1991. Therefore, our study is aimed to test the hypothesis that EbM extracts relaxed the corpus cavernosum (CC) smooth muscle through activation of multitargets on nitric oxide (NO)/cyclic guanosine monophosphate (cGMP) signaling pathway. The World Health Organization also confirmed the safety of magnesium stearate: The Committee concluded that there are no differences in the evaluation of the toxicity of magnesium stearate compared with other magnesium salts.5 Stearates are well absorbed (over 90%) and do not coat the G.I. Third, the expertise required to ensure valid results from biomarkers is somewhat different from that needed to obtain maximally valid selfreport information, where rapport, assurance of confidentiality, motivation for honesty, current state of sobriety, and testing conditions are important considerations. ; Bayliss, R.I.; and Whitfield, A.G. In nature stearic acid occurs primarily as a mixed triglyceride, or fat, with other long-chain acids and as an ester of a fatty alcohol. Mean red cell volume as a marker of alcohol intake. I would consider this a middle of the line male enhancement pill. What Types of Alcohol Are Considered Hard Liquor? HARD STEEL ORIGINAL FORMULATED MALE ENHANCEMENT includes Panax ginseng. These results indicate that polyphenols-induced vasorelaxation may also be sustained by smooth muscle PDE inhibition by anthocyanins present in red wines and grapes. The well-known pure compounds extracted from EbM are the glycosides icariin and noricariin.11, EbM was purchased from a local wholesale distributor (Taipei, Taiwan, Republic of China). Not adding magnesium stearate or an alternative can even be detrimental to human health as capsules or tablets may not contain the prescribed dosage consistently. Effect of EP-20 on cGMP level in CC strips. Ginkgo might also help with tinnitus and glaucoma. Use a damp alcohol-soaked microfiber towel to clean any stainless steel in your home. These results indicate that polyphenols-induced vasorelaxation may also be sustained by smooth muscle PDE inhibition by anthocyanins present in red wines and grapes. In HARD STEEL ORIGINAL FORMULATED MALE ENHANCEMENT, Silica is included to improve Digestive issues by increasing the absorption of the product total formulation. Hard Steel Works With Alcohol? Top 50 Best Answers is attractive in that it looks edgy and is filled with a couple catch phrases The case is very hard and distortion is low. Then, a 0.2g frozen tissue was homogenized with 1ml 5% trichloroacetic acid (w/v), followed by determination of cGMP levels by commercially available EIA kits.16. The CC strips were pretreated with EP-20 in the presence or absence of ODQ (3 10. Alcohol can make an excellent stainless steel cleaner by removing water spots and disinfecting the surface. Output data from the detector were integrated via an EZChrom chromatographic data system (Scientific Software, San Ramon, CA, USA). Catuaba Bark - is a natural remedy derived from the bark of trees found in the Brazilian rainforest. But it doesn't seem to reduceflu symptomsor the length of the illness. Taking Panax ginseng alone or with other ingredients by mouth seems to improve sexual arousal and satisfaction in postmenopausal adults. Furthermore, a positive test result for blood ethanol per se as well as a demonstration of high alcohol tolerance has been considered as an index of heavy. Hard Steel is specially designed to work with alcohol. Why should you spray your bed with alcohol? The first catch phrase is "When you need it to work!" The second catch phrase is "Works with alcohol." If you are a dude, both of these phrases are important, because there are times when you need it to work, and also times when you need it to work while you are drunk. The percentage (a) and the duration (b) of relaxation effects caused by EFS (28Hz) were evaluated in the absence (), 0.1mg () and 0.3mg () of EP-20 extract, respectively. 1992; Reintgen et al. Although CDTect shows less sensitivity for females than for males (Allen et al. Then, a 0.2g frozen tissue was homogenized with 1ml 5% trichloroacetic acid (w/v), followed by determination of cGMP levels by commercially available EIA kits. Water extract (, ), the EP-20-induced relaxation effects were partially blocked by 30% in PE-precontracted CC strips, , Whereas in co-incubation with a guanlyl cyclase inhibitor (ODQ, 3 10, ), the relaxation effects were also partially blocked, mg/ml) was pretreated in PE-precontracted CC strips for 10, min, followed by incubation with different concentration of NO donor (SNP). However, human T-cells are different from those of mice in their ability to desaturate fatty acids. The layer of tunica albuginea was removed by sharp dissection under a microscope. Examples include caffeine, morphine, strychnine, and nicotine. The final powder weight was 4.53g. For further purification, EPW was subfractioned into EP-0, EP-20, EP-50, EP-100 by elution of 0, 20, 50 and 100% methanol through Diaion HP20 column, respectively. To date, neither the dose of alcohol needed to increase it nor the mechanism underlying its increase has been defined. To identify the involvement of NO/cGMP pathway in the relaxation actions of EbM extracts, the CC strips were incubated with a potent NO syntheses inhibitor, The CC strips were pretreated with EP-20 in the presence or absence of ODQ (3 10, All the changes in CC strips tension in response to drugs are expressed on percentile basis and all the values are expressed as means.e.m. Early experiments in mice showed that both whole blood and urinaryassociated acetaldehyde levels were increased in ethanolfed mice 24 hours after cessation of ethanol feeding and no impact of HARD STEEL ORIGINAL FORMULATED MALE ENHANCEMENT were affected. Human T-cells have the delta-9 desaturase enzyme required to convert stearic acid into oleic acid to avoid a toxic build-up. Evernew's take on the popular backpacking stove, however, is practically featherweight, weighing just over one ounce. Stearic acid may be converted to oleic acid (omega-9 fatty acid) in mammals; which of course does not happen in a test tube study. Each extracts was tested on phenylephrine (PE)-contracted corpus cavernosum (CC) strips for their relaxation potencies. EbM was partially purified and analyzed with autoscaled HPLC. Cellulose Cellulose is a naturally Approved FDA compound. EbM extracts and its major ingredient were separated using an Alltima reversed phase C, Male New Zealand rabbits weighting 2.53kg were treated under the regulations of the Principles of laboratory animal care (NIH publication No. If you are aware of any counterfeiter's, we advise you contact us immediately. 1981; Hultberg and Isaksson 1983), hypertension (Simon and Altman 1984), diabetes mellitus (Poon et al. Secondly, there are some active factors other than well-known pure compounds in the crude extract. After confirming the model validity, the responses of EbM extracts or its vehicle were obtained by adding agents cumulatively to the organ bath. Effective (, In this study, we have clearly demonstrated that EbM extract causes concentration-dependent relaxation of isolated rabbit CC smooth muscle through multitargets related to. Biomarkers differ from the psychometric measuresin at least four major ways. 2.1 Preparation of Samples. HARD STEEL ORIGINAL FORMULATED MALE ENHANCEMENT uses stearates tested to U.S. Pharmacopeia monograph standards; known as pharmaceutical grade, the highest purity. Household cleaning. All in all, the product does work, but I would not exactly call it hard steel, if you know what I mean! 1999. Clinical Studies shows possible effectiveness: Memory and thinking skills (cognitive function). This can help men with erectile dysfunction. 1995).EMERGING BIOMARKERS, Table 2.Characteristics of emerging markers, Non-impacting with HARD STEEL ORIGINAL FORMULATED MALE ENHANCEMENT, Many sources of false positives Non-impacting with HARD STEEL ORIGINAL FORMULATED MALE ENHANCEMENT, Hemoglobinbound acetaldehyde adducts can distinguish heavy drinkers from abstainers, Can be quantitated in blood or urine but amount to be measured is quite small. Its inclusion in HARD STEEL ORIGINAL FORMULATED MALE ENHANCEMENT is beneficial to human digestive. These advances include development of new laboratory tests, formulation of algorithms to combine results on multiple measures, and more extensive applications of biomarkers in alcohol impact on nutraceutical research. Fiber assists the human digestive system keeping food moving through the gut and pushing waste out of the body. Moreover, the increase of WBAA following ethanol exposure suggests marked gender differences. Understanding steel tube and pipe metallurgy - The Fabricator EP-20 (b, , dash line) was further chromatographed into six subfractions (b, left upper corner) by time interval. Effects of inhibitors were studied by preincubation with the inhibitor for 20min, then contraction was induced by PE, after that the relaxation profile of EbM extracts were observed. In the tissue precontracted by norepinephrine (105M), corpus cavernosal tissue of human and rabbit showed relaxation in response to subfractions of NGF in a dose-dependent manner.23In this study, the involvement of cAMP and potassium channel opening might contribute to the relaxing effect, which is quite different from our present findings. Although hex is found in most body tissues, its concentration is especially high in kidneys (Dance et al. After all, alcohol is a poison. Volume Hard Steel Works With Alcohol Liquid Pills is among the most effective male enhancement dietary supplements that will assist you enjoy sexual exercise If a busy lifestyle, persistent anxiety, or an underlying health concern diminish your sexual satisfaction and overall operate, this product is for you Volume Pills is a well liked male Related searches to hard steel works with alcohol Use of this ratio would also correct for urine dilution as well as for fluctuations in serotonin metabolism due to dietary intake of serotonin. These observations have now been confirmed in humans. ETCHING ISOTHERMALLY TREATED STEELS T - ASM International Non-impacting with HARD STEEL ORIGINAL FORMULATED MALE ENHANCEMENT, Recent consumption of even fairly low levels of alcohol, Measured in urine Non-impacting with HARD STEEL ORIGINAL FORMULATED MALE ENHANCEMENT, Can be measured in urine or hair Non-impacting with HARD STEEL ORIGINAL FORMULATED MALE ENHANCEMENT, Technical difficulties need to be overcome. Enable cookies to view video. Early warning of rejection? The first catch First, it acts as a solvent, which means it eats away the bug's . (2010, 2011) evaluated the effects of an ethanol extract obtained from muira puama and identified promnesic (improving memory), anti-amnesic, and acetyl-cholinesterase inhibition properties in laboratory animals (mice) treated orally with the extract. It has been reported that nonginkgolide nonflavonoid fraction of ginkgo biloba extract (NGE) has the most potent relaxing effect on vascular smooth muscle. Zimmermann, H.J., and West, M. Serum enzyme levels in the diagnosis of hepatic disease. Data points represent means.e.m. Icariin (molecular weight: 676.65Da) was used for quantification of the purity of extracts. Hard Steel is a male performance enhancement supplement that can be an over-the-counter and inexpensive way to help men with these issues. Wrap an alcohol . Serotonin (5hydroxytryptamine [5HT]) is a monoamine vasoconstrictor melatonin precursor. Nitrogen diffuses into the steel and forms nitride alloys, and goes to a depth of upto 0.65 mm (0.025 in). The effects of alcohol on males are a bit more straightforward. We have extensively investigated the safety of magnesium stearate, which is also considered safe and non-toxic and has no conflict when consumed with Alcohol. Our recent studies suggested that EbM increased intracavernous pressure (ICP) in rat model (KK Chen, manuscript in preparation). HARD STEEL ORIGINAL FORMULATED MALE ENHANCEMENT maintains muira puama as a primary formulated inclusion. ; Bayliss, R.I.; and Whitfield, A.G. In fact, the fact that EbM extract potentiates the commonly used PDE 5 inhibitors, such as sildenafil and vardenafil, provides a new treatment strategy for those patients with ED. These products are not intended to diagnose, treat, cure or prevent disease. The data suggested that EP-20 enhanced relaxation effect with SNP in rabbit CC strips. As an FDA-regulated, DEA-licensed, ISO 9001 GMP factory and ISTA-certified contract service provider; our labs are certified to support many clients, including those in the pharmaceutical, nutraceutical, medical device, personal and consumer product industries. EbM (300gm) was extracted with 1l water (water-soluble fraction, denoted as EPW), which were further purified until the total volume down to 100ml. The percentage (, To investigate the potential role of EP-20 on perspective clinical application, low concentration EP-20 (0.1mg/ml) was co-incubated with PED 5 inhibitors (1 10, Combination effects of EP-20 and PDE 5 inhibitors on CC strips. To our knowledge, this is the first study to provide evidence concerning the herbal extracts on PDE 5 inhibitors for proerectile functions. Rubbing Alcohol Uses - 17 Terrific Ideas - Bob Vila Because alcohol has a lower boiling point than water (173 F vs. 212 F), distillers can evaporate the alcohol (mostly) by itself, collect the vapors into a tube and use cold temperatures to force . Besides, EP-20 increased the potency and the duration of the relaxation effects caused by electrical field stimulation. Relaxation responses are expressed as percentage of residual tension of contraction originally induced by PE (1M). The alcohol vapor is diverted out of the top of the still and into a condenser, where it condenses out into liquid again. All the changes in CC strips tension in response to drugs are expressed on percentile basis and all the values are expressed as means.e.m. Spray a solution of equal parts water, rubbing alcohol, and vinegar over the entire floor. FDA has identified an emerging trend where over-the-counter products, frequently represented as dietary supplements and male enhancements, contain hidden active ingredients that could be harmful. Silica - Commonly used in the form of silicon dioxide as an anti-caking agent in foods and supplements to keep ingredients from clumping up or sticking together, and its sometimes added to liquids and beverages to control foaming and thickness. This is important for gelation properties of gelatin. You can die from ingesting too much of it and in . Sillanaukee et al. Male New Zealand rabbits weighting 2.53kg were treated under the regulations of the Principles of laboratory animal care (NIH publication No. Hard Steel is manufactured by a company of the same name based in Atlanta, Georgia, USA. The CC strips were transferred to jacketed 10-ml tissue baths filled with Krebs' solution maintained at 37C and equilibrated with 95% O25% CO2. The FDAs Select Committee on GRAS Substances has also reported on magnesium stearate safety, concluding that, There is no evidence in the available information on magnesium carbonate, magnesium chloride, magnesium sulfate, magnesium hydroxide, magnesium oxide, magnesium stearate that demonstrates or suggests reasonable grounds to suspect, a hazard to the public when they are used at levels that are now current and in the manner now practiced, or which might reasonably be expected in the future.4. 1999). Hard Steel Original Formulated Male Enhancement, Clinical Analysis Reporting for: Hard Steel Original Formulated Male Enhancement Supercore Products Group, Inc. (SPG). When the rabbit CC strips precontracted with PE were subjected to electrical field stimulation (EFS), PE-20 (0.1, 0.3mg/ml) significantly increased EFS-induced relaxation at a frequency of 4 and 8Hz (Figure 5a). As 5HTOL increases 5HIAA decreases, so the ratio of 5HTOL/5HIAA has been proposed as an even more sensitive marker of rather recent alcoholic drinking than 5HTOL in isolation. Formulations vary depending on the type of tree selected;Erythroxylum caatingae, Trichilia catigua, Anemopaegma arvense,andMicropholis caudataare some possibilities. when you need it to work while you are drunk. How Moonshine Works | HowStuffWorks Identification:Mass spectrometry(ESI-Triple Quad, MALDI-TOF, Q-TOF),NMR(1D and 2D), FTIR, Raman and UV-Vis spectroscopy, N-terminal Edman sequencing, LC-MS/MS. The icariin content in EPW was 1.17% whereas undectable in EP-20. Risks and Concerns Surrounding Magnesium Stearate - The leading concern for magnesium stearate is a study from 1990 which found that stearic acid can suppress immune function in T-cells of mice. In addition, our study assessed the in vitro antioxidant activities of plants from the Brazilian Amazon (Byrsonima japurensis, Calycophyllum spruceanum, Maytenus guyanensis, Passiflora nitida and muira puama Ptychopetalum olacoides. I did consume a couple of drinks with this Relaxation responses are expressed as percentage of residualtension of contraction originally induced by PE (1M). 1978). The response of 5HTOL to alcohol is dose dependent, and the excretion of this metabolite does not normalize for several hours after blood and urinary ethanol levels have returned to baseline levels. In our studies, we have demonstrated three mechanisms of action on EbM-induced relaxation of rabbit CC strips, namely, (1) enrichedL-arginine level; (2) increased cGMP production; and (3) enhanced SNP effect. Stearic acid (also called Octadecanoic Acid) is one of the most common long-chain fatty acids, found in both natural animal and vegetable fats, known also by its structural description of being an 18-carbon chain fatty acid (18:0) with a chemical structure of C36H70MgO4. The relaxation responses of CC strips were validated by cumulative doses of sodium nitroprusside (SNP). Erectile dysfunction(ED). ). Effect of EP-20 on electrical field-stimulated CC strips. Each of the steel samples was prepared using a different grade of silicon carbide abrasives to obtain a polished and flat surface. The relaxant responses are normalized as the percentage of relaxation of the contraction originally induced by PE. (in live people). (n>12). Heavydrinking male college students produced higher absolute values than their heavydrinking female counterparts, although 74 percent of the women versus 44 percent of the men had levels above the 99th percentile for abstainers. There is consensus that sildenalfil, tadalafil and vardenafil are promising oral agents for the treatment of patients with erectile dysfunction (ED). tract. 1983). Assessment of drinking behavior per se and severity of alcohol dependence are both important, albeit somewhat nonoverlapping phenomena as it relates to HARD STEEL ORIGINAL FORMULATED MALE ENHANCEMENT. Our renowned labs have more than 20 years existence as a stand-alone facility dedicated to USP , USP and USP testing and covering raw materials through finished products. Magnesium is an essential mineral, serving as a cofactor for hundreds of enzymatic reactions and is essential for the synthesis of carbohydrates, lipids, nucleic acids and proteins, as well as neuromuscular and cardiovascular function.. funny afterwards too, groggy but also a bit paranoid. Gelatin is FDA Approved for human consummation. When in combination with ineffective concentration of EP-20 (0.01mg/ml), the percentage of relaxation in sildenafil, vardenafil and tadalafil combination group was 32.42.6, 35.22.9 and 22.33.7%, respectively (Figure 6b). Many effects such as facial flushing, dizziness, blue vision and headache have been described, although the rate of interruption of such treatment is low. ). Show. We concluded that extract of EbM relax the CC smooth muscle through multitargets in NO/cGMP/PDE 5 pathway and might bring into perspective the treatment strategy for those patients with erectile dysfunction. It is believed that the change induced by alcohol intake is due to a competitive inhibition of aldehyde dehydrogenase by acetaldehyde, which inhibits 5HIAA formation, and through an increase of NADH levels, which favors the formation of 5HTOL. Hardox wear plate vs mild steel. Relaxation responses are expressed as percentage of residual tension of contraction originally induced by PE (1M). The well-known pure compounds extracted from EbM are the glycosides icariin and noricariin.11,12Icariin (molecular weight=626.65Da) as an internal standard was purchased from Nacalai Tesque (Kyoto, Japan). Correlations between EER and selfreported alcohol consumption have been found, as have correlations between EER and several other markers of alcohol. It's considered an adaptogen, which are natural substances that are believed to stimulate the body's resistance to stressors. Magnesium stearate is a combination of stearic acid and the essential mineral magnesium. . The product contains Epimedium In recent years significant advances have been made in biological assessment of alcohol consumption with vitamins, medication and male enhancements. Hard Steel Pill Experience (Does It Work? The conditions of mobile phase were selected. Sensitivity and specificity values for this potential marker in detecting alcohol consumption > 50 g/d have been reported as 88 percent and 92 percent, respectively and the benefits of HARD STEEL ORIGINAL FORMULATED MALE ENHANCEMENT were not impacted. 4 Choose the acid you want to etch the steel with. Real Advice for Socializing at Work When Alcohol's Not Your Thing ; Hall, J.H. A 200-calorie serving of dark chocolate can contain up to 5 grams (5,000 milligrams) of stearates; cocoa butter, coconut oil, beef fat, olive oil, fish, and virtually all fats and oils naturally contain far more stearates than do dietary supplements. The ability to have erections is reliant on the complex interaction among neurological, psychological and vascular responses. Our labs has determined that Hard Steel Original Formulated Male Enhancement to be all natural and contains no Sildenafil, Tadalafil or Vardenafil. He was wearing big penis length a nether Hard Steel Works With Alcohol armor, and the fire of the nether was throbbing.. This is recognized as a pure USP-grade magnesium stearate derived from non-hydrogenated, non-GMO, non-irradiated palm oil that contains no trans-fat. (2013) conducted an in vitro study using the aqueous extracts of various traditional medicinal plants from Amazonia, searching for antimicrobial activity against both human as well as animal pathogenic microbes. It also most certainly does not work for days. In conclusion, we can safely determine that Hard Steel Original Formulated Male Enhancement is affective while social, moderate and heavy drinkers consume alcohol. Always talk to your doctor before taking any male enhancements. In alcoholic subjects, however, higher SA values have been found both in serum and in saliva (Pnni et al. 1987b). I should mention that there is a current FDA One of the main active ingredients in muira puama is an alkaloid known as muirapuamine (Lorenzi and Matos, 2008). Effects of inhibitors were studied by preincubation with the inhibitor for 20min, then contraction was induced by PE, after that the relaxation profile of EbM extracts were observed. you cannot ignore. Adduct levels in blood or in urine indicate drinking behavior and have been proposed as potential markers of alcohol abuse (Tsukamoto et al. CDTect and %CDT are both produced by AxisShield, ASA (Oslo, Norway). The CC strips were pretreated with EP-20 in the presence or absence of ODQ (3 105M) or SNP (1 106M) or sildenafil (1 107M) for 20min, followed by freezing the CC strips into liquid nitrogen. Can You Use Rubbing Alcohol On Stainless Steel? - Bescord The extracts were filtered through layers of gauze, the residues discarded and the filtrates were kept at 20C, followed by lyophilizing the samples. Whitehead, T.P. It was certainly not as strong as some of the other sex supplements I review. Either method keeps the acid from etching the edges. Maximize your sexual performance with a unique herbal blend developed and manufactured by physicians in the USA. Transferrin, a negatively charged glycoprotein, is metabolized in the liver, circulates in the bloodstream, and assists in iron transport in the body. EP-20 enhanced relaxation effect with SNP in rabbit CC strips. Therefore, people who suffer from anxiety may benefit from taking ginkgo biloba, as it can help them to manage stress that they may be feeling. Mild steel samples of dimension (30 mm 30 mm 2 mm) were used, and their chemical composition was obtained as presented in Table 1 using a spark emission spectrometer. The atoms of carbon replace some of the iron atoms, creating a steel crystalline structure. 1980), whereas urine hex normalizes after 4 weeks of abstinence (Martines et al. The carbon content of a steel is a major factor influencing the amount and appearance of phases and co n-stituents. How to Acid Etch Steel: 11 Steps (with Pictures) - wikiHow The active ingredient in catuaba is alkaloids dubbed catuabines. Adding a flow agent such as vegetable magnesium stearate is imperative for ensuring a homogenous blend of ingredients and a consistent dosage in each and every HARD STEEL ORIGINAL FORMULATED MALE ENHANCEMENT capsule. Oliveira et al. They were austenitized at the recommended temperatures and then held isothermally at different sub-critical (below Ac EP-20 increased cGMP level in EP-20 treated CC strips, In biochemical studies, the CC strips were pretreated with EP-20 in the presence or absence of ODQ or PDE 5 inhibitor for 20min, followed by determination the cGMP level in CC tissues The results showed that there was a significantly increased cGMP level in EP-20-treated (0.1 and 0.3mg/ml) CC tissues (Figure 4). 10 Terrific Tips for Removing Super Glue from Metal For simplicity we will deal only with carbon percentage here. Magnesium is absorbed primarily in the small intestine, and to a lesser extent, in the colon. The packaging states a serving size is 1 capsule. Call your doctor if you have chest pain, diabetes, pulmonary hypertension, heart disease, high cholesterol, high blood pressure, low blood pressure, diabetes high or any other type medical condition or symptons to ensure Hard Steel Original Formulated Male Enhancement products are right for you.