2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. In clinical studies, people who took Injectafer had their hemoglobin level improve as early as 35 days after receiving treatment. Does Venofer Vial interact with other medications? Pain, swelling, or redness at the injection site may occur. This may be helped by giving the medication more slowly or at a lower dose. There are different types of anemia, but IDA is the most common type. If you notice other effects not listed above, contact your doctor or pharmacist. Sharing this information can help you avoid potential interactions. Injectafer contains the active drug ferric carboxymaltose, while Feraheme contains the active drug ferumoxytol. Brand-name medications usually cost more than generics. Talk with your doctor. So theres no recommended pediatric dosage for Injectafer. signs of inflammation in the lining of your stomach --pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. IQVIA [NSP Audit from MAT November 2013 to November 2018]. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Injectafer isnt a medication that youll take regularly on a schedule. This is not a list of all drugs or health problems that interact with this medicine. . With IDA, you have low hemoglobin levels. And this would give you a total cumulative Injectafer dose of 1,440 mg. Injectafer should be given in two doses. Before using iron sucrose, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Venofer is used to treat iron deficiency anemia in people with kidney disease. But its only approved for use in people with CKD who may or may not need dialysis. Drug interactions may change how your medications work or increase your risk for serious side effects. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. These side effects may include constipation and diarrhea. Venofer may cause serious side effects including: problems with your dialysis vein access point, chest pain, severe headache, blurred vision, pounding in your neck or ears, lightheadedness, pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, and fever Get medical help right away, if you have any of the symptoms listed above. When the toxins are released into the air, they can be inhaled and cause irritation to the lungs. Dr. Colby holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford Universitys Graduate School of Business, and a degree in Genetics with Honors from the University of Michigan. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. I was surprised too but the Dr said it definitely sounds like a reaction. With slow IV injection, the drug is given as a single, slow injection into your vein. experience severe side effects, please seek medical attention right away and notify the ordering physician. Common side effects of Venofer include: muscle cramps, nausea, vomiting, stomach pain, strange taste in the mouth or decreased sense of taste, diarrhea, constipation, headache, cough, sore throat, sinus pain, congestion, back pain, joint pain, dizziness, weakness, tired feeling, anxiety, ear pain, swelling of the arms/legs, or Dilute Venofer in a maximum of 250 mL of 0.9% NaCl. Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. Injectafer contains the active drug ferric carboxymaltose. Boxed warnings alert doctors and patients about drug effects that may be dangerous. Have blood work checked as you have been told by the doctor. Many people using this medication do not have serious side effects. The researchers looked to see how well each drug worked to increase peoples hemoglobin level. Some products that may interact with this drug include: vitamin products, other iron-containing products. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. Mild side effects of Injectafer can include:*. Learn about uses, cost, how it works, and more. Hes an expert in genetic testing, genetic analysis, andprecision medicine. If you do breastfeed while youre taking Injectafer, the drugs manufacturer recommends that you monitor your child for side effects of the drug. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. After getting each dose of Injectafer, your healthcare professional will monitor you for at least 30 minutes. It's a more immediate treatment than supplements or dietary changes. As a result, you may not make as much EPO as usual. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. Its FDA-approved to treat iron deficiency anemia (IDA) in adults. You may need extra iron because of blood loss during kidney dialysis. Symptoms of a severe allergic reaction can include: Because of the risk of allergic reaction with Injectafer, your healthcare professional will monitor you for at least 30 minutes after you get each dose of the drug. After the infusion, you can drive yourself home and return to your usual activities. Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your . It belongs to a class of medications known as iron replacement products. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. All patients receiving Venofer require periodic blood tests to monitor the amount of iron in the blood. Injectafer contains the active drug ferric carboxymaltose. Examples of thisinclude: Not allside effectslast forever. Some people may also experience skin irritation from the adhesive tape and other medical equipment used during the procedure. Consult your pharmacist or local waste disposal company. Learn how to store and discard medical supplies safely. Do not exceed 1,500 mg of iron per dosing course. Talk to your pharmacist for more details. Terminal half-life ranges from 7 to 12 hours. Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. Potential side effects that are usually mild may include, but are not limited to: Headache Nausea Dry Mouth Stomachache Dizziness Diarrhea Constipation These side effects may not impact life too much and may only be temporary. People with IDA have low blood levels of hemoglobin. Cancer patients who have anemia and are taking an ESA. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. I got Venofer twice in the last few years and now my iron deficiency is worse than ever, first time my hemoglobin is down to 11,2. Do not use Injectafer in people with a history of hypersensitivity reactions to Injectafer or any components of the drug product. If you have iron deficiency anemia (IDA), consuming moderate amounts of alcohol may be safe, if your doctor tells you its OK. (With IDA, you have a low level of red blood cells thats caused by not having enough iron.). Keep all drugs in a safe place. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Together, they can recommend ways to help you manage a body weight thats healthy for you. Injectafer is available only as a brand-name medication. People with IDA have low blood levels of hemoglobin. Last updated on Feb 20, 2023. In clinical trials,. The infusion will take between 15-30 minutes if it is given in. Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. Notify your healthcare provider of any irritation at the injection site. Drug interactions: DayQuil can interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. Here's some detail on certain side effects this drug may cause. Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. During pregnancy, this medication should be used only when clearly needed. A lack of iron can lead to iron deficiency anaemia if left untreated. }|54U|O~?|_v;f\o^(W+/-|^)O65_)rd sm }[x[)y.z Wz?9_jV0ub,`g`s?oXOSp/Kgw$b!Vb$;IvBVR9n|\0ln=;/=,mgw@do,[";/8nJL{n}Bb-|^6[~>a_1H'^M:^vv=iM+x|+Y But its important to note that these studies werent designed to show whether Injectafer is safe to use during pregnancy. Do not start, stop, or change the dosage of any medicines without your doctor's approval. For people with certain medical implants, such as pacemakers, an MRI may pose an . However, to be safe, tell your doctor or pharmacist about all prescription, over-the-counter, and other drugs you take before taking Injectafer. So we cant say for sure whether the drug is safe to use while youre pregnant. Call your doctor for medical advice about side effects. If your symptoms or health problems do not get better or if they become worse, call your doctor. Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. For people weighing 50 kg (about 110 lb) or more, administer Injectafer in two doses of 750 mg, at least 7 days apart. The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. Be ready to tell or show what was taken, how much, and when it happened. Some drugs may have another patient information leaflet. Venofer is not for treating other forms of anemia not caused by iron deficiency. Do not double the dose to catch up. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. I used to get a different type but my . In some cases, they may even recommend that you use a drug other than Injectafer to treat your anemia. Is the ketogenic diet right for autoimmune conditions? Change in taste. MNT is the registered trade mark of Healthline Media. This way, if you have an allergic reaction to Injectafer, your healthcare professional can treat your reaction. In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. %PDF-1.3 Venofer treatment may be repeated if iron deficiency reoccurs. And if you dont have an allergic reaction to your first dose of a drug, its typically safe to assume you wont have an allergic reaction to doses that follow. reactions at the site of the injection. Innovators Monograph Discuss the risks and benefits with your doctor. This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. As with most drugs, some people can have an allergic reaction after taking Injectafer. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Source: Wolters Kluwer Health. This medication is given by injection into a vein as directed by your doctor. But you dont necessarily need to eat these foods unless your doctor tells you to do so. Possibleside effectsareweight gainand suicidal thoughts. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. Its responsible for carrying oxygen throughout your body. Canada residents can call a provincial poison control center. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. If the underlying cause of your anemia isnt addressed, theres a chance your anemia could come back after Injectafer treatment. Does Venofer Vial interact with other drugs you are taking? The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. Many patients with kidney disease cannot get enough iron from food and require injections. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. And theyll recommend how soon after starting the drug you need to have this level checked. Follow your doctor's directions carefully. * Feraheme has a boxed warning for this side effect. Its possible to get rid of or reduce the severity ofside effects. With slow IV injection, the drug is given as a single, slow injection into your vein. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. If a person does not have an allergic response or any other unanticipated reactions, a doctor will administer the remaining iron. Following an LSD trip, users may experience a sort of 'comedown.'. Here we look at how Injectafer and Feraheme are alike and different. With this condition, you also have a low hemoglobin level. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. Usually, but not always, the bigger a person is the slower it takes for drugs to break down and leave the body. However, diarrhea it isnt very common in people using Injectafer. You may also report side effects at https://www.fda.gov/medwatch. Pain, swelling, or redness at the injection site may occur. Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. (A generic drug is an exact copy of the active drug in a brand-name medication.). And the drug has also been studied in children with IDA who have inflammatory bowel disease (IBD). Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. Do not flush down a toilet or pour down a drain unless you are told to do so. Here are answers to some frequently asked questions about Injectafer. fever. If you have questions about using Injectafer for anemia during pregnancy, talk with your doctor. Side effectswill last a very long time if the cause of them is not resolved. It depends. Throw away unused or expired drugs. Back pain. Most of these side effects may go away within a few days or a couple of weeks. 2023 Medicine.com All rights reserved. * This is a partial list of mild side effects from Injectafer. An example of a drug interaction that many people are not aware of isgrapefruitjuice and statins. Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. Best food forward: Are algae the future of sustainable nutrition? On day three I had a headache and felt heavy/exhausted, which lasted a few days. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. Phosphorus also helps your nerves function properly. Your body then uses the iron from Injectafer to make hemoglobin and new RBCs. Venofer also comes as a liquid thats given by either IV infusion or a slow IV injection. TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. If youre interested in finding an alternative to Injectafer, talk with your doctor. These tests will help make sure Injectafer is working to treat your iron deficiency anemia (IDA). Why is the range so wide? Available for Android and iOS devices. If this happens to you, your doctor may recommend that you receive another treatment course of Injectafer. Side effects like nausea and low blood pressure are common with most iron infusions. Other drugs are available that can treat iron deficiency anemia (IDA). These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. Serious side effects should be reported to a physician and/or PharmD for medical advice. If you have more questions about how Injectafer will affect your anemia, talk with your doctor. Your doctor will determine the best dosage to fit your needs. Feraheme also comes as a liquid thats given by IV infusion. Some people only need one treatment course of Injectafer. The oral form of the drug, called sucroferric oxyhydroxide and used . This is only a brief summary of general information about this medicine. In clinical studies, Injectafer was effective in treating IDA in adults who either didnt improve with or had side effects from taking iron by mouth. Injectafer isnt known to interact with any other medications, herbs, supplements, or foods. Injectafer and Venofer can cause very similar side effects, but some different ones as well. With IV infusion, the drug is given as a slow drip into your vein over a period of time. Instead, youll start by receiving just one treatment course of Injectafer. <> other treatments you receive, you will need to go back for several treatments with Venofer. 5 0 obj WebMD provides common contraindications for Venofer Vial. These include: Note: For more information about the potential negative effects of Injectafer, see the Injectafer side effects section above. Pain in your limbs. Check with your pharmacist. You can also write a reminder on your calendar. Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. Or your doctor may recommend that you change your eating habits to include more iron in your diet. This gives a total cumulative dose of 1,500 mg of Injectafer. Things to remember when you fill your prescription. "The most common side effects to COVID vaccines include pain at the injection site, fevers, chills, nausea, headaches, tiredness, and painful or swollen lymph nodes in the arm where the vaccine. Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. I actually was constipated after my 3rd but didn't think anything of it. In one study, people were given either Injectafer or an iron replacement drug called Venofer. There have also been reports of serious allergic reactions to Venofer. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. *Patients are calculated based on an estimated annual cumulative dose. Its caused by your body not having enough iron, which is needed to make hemoglobin. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. They can give you tips on how to deal with any side effects that may be bothersome. If you have questions about drinking alcohol while youre taking Injectafer, talk with your doctor. Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. Someside effectsare temporary or last as long as the person continues takingprescription medicine. Keep in mind that the risk of certain pregnancy-related problems can be increased if iron deficiency anemia (IDA) is left untreated. In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. Theseside effectsmay last as long as they are undercancer treatment. It can be given as a slow injection over 2 to 5 minutes or as an infusion. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. Undergoingcancer treatmentwithradiation therapyorchemotherapy drugsmay result inhair loss, which can be devastating to somepeople. * Sex and gender exist on spectrums. The drug helps increase your hemoglobin level back to a value thats within the normal range. It is given into a vein for a period of time. Injectafer comes as a liquid thats given by either intravenous (IV) infusion or slow IV injection. Find out what health conditions may be a health risk when taken with Venofer Vial reese0809 1 yr. ago. Do not share your drugs with others and do not take anyone else's drugs. With CKD, your kidneys dont function properly, which can lead to your body having problems using iron. Venofer pregnancy and breastfeeding warnings. Orofer S 50 Injection 1 Injection in 1 Packet 147. But for other people, their anemia may come back after Injectafer treatment. Theseeffects of medicine on thebodycan also lead to medication non-compliance and worsening of themedical conditionthey are meant to treat. These lists contain examples of serious side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). Storage Condition Store in a cool and dry place protected from light. Remember that it is best to get your vitamins and minerals from food whenever possible. Mental healthdisorders like depression may requireantidepressantsto treat. However, side effects at the 150 mg dose may indicate that you might not . But so far I feel better than before the infusion. Its because everyones body is different. Venofer® (iron sucrose injection, USP) is available by prescription only. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). Heart failure: Could a low sodium diet sometimes do more harm than good? fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing They can recommend if this is safe for you to do. For additional information, contact your healthcare provider. dizziness. After receiving IV iron therapy, you will be monitored for 30 minutes to make sure you do not have an allergic reaction or a drop in blood pressure. Dizziness. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. A shortage of iron can cause health problems. 12 Medicines That Could Help, List Venofer Vial side effects by likelihood and severity. But keep in mind that in this study, delayed allergic reaction only occurred in one person. This is not a complete list of side effects and others may occur. Phosphorus is an electrolyte that your body needs in order to make energy. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. For some people, it may be OK to continue taking a multivitamin that contains iron. Get emergency medical help if you have signs of an allergic reaction to Venofer: hives, rash, itching; feeling light-headed; difficulty breathing; swelling of your face, lips, tongue, or throat. Clinical trials showed that Injectafer is effective in increasing hemoglobin levels in people with iron deficiency anemia (IDA). However, be sure to take the dosage your doctor prescribes for you. Injectafer can cause low blood levels of phosphorus, which is a condition called hypophosphatemia. If needed, theyll recommend treatment, including certain medications. All of the people took iron by mouth for 2 weeks. (For more information on Venofer, see the Injectafer vs. Venofer section above). Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; If you have questions about side effects, call your doctor. For instance, someone with lowblood pressuremay receive a medication to prevent migraines that lowersblood pressure, this may causeseriousside effects. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. Learn how to store and discard medical supplies safely. Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. Administer Venofer in 3 divided doses, given by slow intravenous infusion, within a 28 day period: 2 infusions each of 300 mg over 1.5 hours 14 days apart followed by one 400 mg infusion over 2.5 hours 14 days later. Treatment with Venofer injections can make it harder for your body to absorb iron medications you take by mouth. This survey is being conducted by the WebMD marketing sciences department. This medication passes into breast milk. Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. Taking a larger dose of LSD can extend the duration of the trip, but generally, the main effects of LSD don't tend to last any longer than 12 hours. Also tell them about any vitamins, herbs, and supplements you use. This may lead to the person needing a higher dose compared to someone who is muchsmaller.