This fragrant, perennial plant -- a member of the celery family -- has smooth purplish stems and umbrella-shaped clusters of white flowers and winged fruits in July and August. Electronic Code of Federal Regulations. Eur J Dermatol. Effect of preoperative licorice lozenges on incidence of postextubation cough and sore throat in smokers undergoing general anesthesia and endotracheal intubation. Sigurjonsdottir HA, Franzson L, Manhem K, et al. Drug Metab Dispos 2002;30:709-15.. View abstract. Nussbaumer, U., Landolt, M., Rothlisberger, G., Akovbiantz, A., Keller, H., Weber, E., Blum, A. L., and Peter, P. [Postoperative stress hemorrhage: ineffective prevention with pepsin inhibitor and deglycyrrhizinized licorice extract. Botanical names: Paeonia lactiflora, Paeonia suffruticosa, Paeonia veitchii How It Works Peony contains a unique glycoside called paeoniflorin. Removes excess melanin: Licorice extract brightens the skin in another way, too. Cardiovasc.Drugs Ther 1998;12(6):599-600. 1999;15:499-523. Medicinal herbs: modulation of estrogen action. Shen, A. Y., Wang, T. S., Huang, M. H., Liao, C. H., Chen, S. J., and Lin, C. C. Antioxidant and antiplatelet effects of dang-gui-shao-yao-san on human blood cells. Some research studies have found Angelica Sinensis to be beneficial for its effects on some symptoms of menopause. Learn more about Peony health benefits, uses, side effects, effectiveness, safety, precautions, and warnings. Licorice might decrease how quickly the body breaks down methotrexate. $9.44 $ 9. Lancet 1990;335(8697):1060-3. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Cai Y, Yuan Q, Xu K, et al. Contact Dermatitis 2021;85(4):454-455. . J Pharmacobiodyn 1983;6:153-60. . Harada M, Suzuki M, Ozaki Y. J Clin Pharm Ther 2002;27:229-30. . View abstract. Biol Pharm Bull 2007;30(11):2191-2195. View abstract. 2001;21(7):501-503. Ned.Tijdschr Geneeskd. 2007;30(10):1898-1904. Kamei T, Kumano H, Iwata K, et al. Licorice might decrease how well cisplatin works. J Pharm Pharmacol 2003;55:1275-82. Fugh-Berman, A. Herb-drug interactions. I like herbal and fuit teas and a particular favourite of mine contains liquorice. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. View abstract. Objective: To evaluate the effect of different ratio of peony and licorice and Christina Loosestrife herb decoction on isolated in New Zealand . View abstract. Moghadamnia, A. Liang, R., Chen, M. R., and Xu, X. Part 2: Effect of glycyrrhizic acid on the course of illness]. Hussain RM. View abstract. Advancing combination treatment with glycyrrhizin and boswellic acids for hospitalized patients with moderate COVID-19 infection: a randomized clinical trial. Cancer Res 2000;60:5704-9.. View abstract. The anti-estrogenic action of beta-glycyrrhetinic acid. Scand.J Gastroenterol. Baba, M. and Shigeta, S. Antiviral activity of glycyrrhizin against varicella-zoster virus in vitro. Because of its beneficial effects, the licorice root has been dubbed the "Medicinal plant of 2012." Now scientists have discovered that licorice root from the papilionaceae or leguminous family . Health Care Women Int. Effect of Shakuyaku-kanzo-to (Tsumura TJ-68) on muscle cramps accompanying cirrhosis in a placebo-controlled double-blind parallel study. Armanini, D., Mattarello, M. J., Fiore, C., Bonanni, G., Scaroni, C., Sartorato, P., and Palermo, M. Licorice reduces serum testosterone in healthy women. View abstract. Peony-glycyrrhiza decoction, an herbal preparation, inhibits clozapine metabolism via cytochrome P450s, but not flavin-containing monooxygenase in in vitro models. View abstract. View abstract. Some sources claim that it's contraindicated during pregnancy . View abstract. View abstract. Side effects of peony tea! The dose of your warfarin might need to be changed. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Brush, J., Mendenhall, E., Guggenheim, A., Chan, T., Connelly, E., Soumyanath, A., Buresh, R., Barrett, R., and Zwickey, H. The effect of Echinacea purpurea, Astragalus membranaceus and Glycyrrhiza glabra on CD69 expression and immune cell activation in humans. Tsuda T, Sugaya A, Ohguchi H, et al. Robles BJ, Sandoval AR, Dardon JD, Blas CA. View abstract. Because licorice has a hormone-like effect, it can relieve excessive gastric acid secretion. Caubet-Kamar, N., Tubery, M., Garrouste, C., Lauque, D., and Kamar, N. Harmful effect of saline infusion in a patient with glycyrrhizic acid poisoning. View abstract. However, taking too much licorice root may cause side effects. View abstract. Total glucosides of peony ameliorates Sjogren's syndrome by affecting Th1/Th2 cytokine balance. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. J Altern Complement Med. Biol Pharm Bull. J Ethnopharmacol 2011;135(1):162-72. J Altern Complement Med 2009;15(4):439-443. Peony-glycyrrhiza decoction for antipsychotic-related hyperprolactinemia in women with schizophrenia: a randomized controlled trial. Taking licorice might reduce the effects of blood pressure medications. Chem Pharm Bull (Tokyo) 1994;42(5):1056-1062. 2010;33(2):321-324. J Agric Food Chem 2012;60(36):9062-73. View abstract. According to research, the combination of . He X, Xing D, Ding Y, et al. Bian, X., Xu, Y., Zhu, L., Gao, P., Liu, X., Liu, S., Qian, M., Gai, M., Yang, J., and Wu, Y. Am J Epidemiol 2001;153:1085-8. The benefits of licorice root can be enjoyed as a tea, supplement, tincture, or topical treatment, and even as candies. Nat Prod Res 2007;21(14):1234-1241. View abstract. J Clin Hypertens (Greenwich) 2008;10:153-7. Hattori, M., Sakamoto, T., Kobashi, K., and Namba, T. Metabolism of glycyrrhizin by human intestinal flora. Black licorice can have serious side effects when eaten in large amounts. 10. 2009;14(1):64-65. Arentz S, Smith CA, Abbott J, Fahey P, Cheema BS, Bensoussan A. Here are a few of them: . Life Sci 9-27-2002;71(19):2267-2277. View abstract. Acharya SK, Dasarathy S, Tandon A, et al. A controlled trial of a dissolving oral patch concerning glycyrrhiza (licorice) herbal extract for the treatment of aphthous ulcers. View abstract. Contact Dermatitis 2008;59(1):52. Du, J. H. and Dong, B. D. [Comparative study on clinical efficacy of using methotrexate singly or combined with total glucosides of Paeony in treating rheumatoid arthritis]. Licorice might increase how quickly midazolam is broken down by the body. 2020;2020:8401239. [Peony tincture in the complex treatment of allergic dermatoses]. View abstract. Nutr Res 2012;32(2):85-92. Tamir S, Eizenberg M, Somjen D, et al. Phytother Res. Researchers from the University of Minnesota studied 50 atopic dogs in a randomized, double-blind, placebo-controlled trial. View abstract. Tu, J. H., He, Y. J., Chen, Y., Fan, L., Zhang, W., Tan, Z. R., Huang, Y. F., Guo, D., Hu, D. L., Wang, D., and Hong-Hao Zhou. Cinatl J, Morgenstern B, Bauer G, et al. Intern Med 2017;56(2):175-9. Zhong.Xi.Yi.Jie.He.Za Zhi. The efficacy and safety of the combination of total glucosides of peony and leflunomide for the treatment of rheumatoid arthritis: a systematic review and meta-analysis. View abstract. Arch.Pharm Res 2012;35(11):1945-1952. A dose of 800 milligrams (mg) or more of licorice root per day has been linked to low potassium levels. Rikknen K, Seckl JR, Heinonen K, Pyhl R, Feldt K, Jones A, Pesonen AK, Phillips DI, Lahti J, Jrvenp AL, Eriksson JG, Matthews KA, Strandberg TE, Kajantie E. Maternal prenatal licorice consumption alters hypothalamic-pituitary-adrenocortical axis function in children. Takahara T, Watanabe A, Shiraki K. Effects of glycyrrhizin on hepatitis B surface antigen: a biochemical and morphological study. View abstract. View abstract. Guo, T. L. and Zhou, X. W. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. J Clin Psychopharmacol 1997;17(3):234-235. View abstract. J Telemed Telecare. View abstract. The yellow-brown thick-branched roots are used as medicine. Kraus SD, Kaminskis A. View abstract. Sakamoto, S., Yoshino, H., Shirahata, Y., Shimodairo, K., and Okamoto, R. Pharmacotherapeutic effects of kuei-chih-fu-ling-wan (keishi-bukuryo-gan) on human uterine myomas. Ann Noninvasive Electrocardiol. Armanini, D., Castello, R., Scaroni, C., Bonanni, G., Faccini, G., Pellati, D., Bertoldo, A., Fiore, C., and Moghetti, P. Treatment of polycystic ovary syndrome with spironolactone plus licorice. View abstract. 2000;20(3):173-175. Feng ZT, Xu J, He GC, Cai SJ, Li J, Mei ZG. View abstract. Man SC, Li XB, Wang HH, et al. View abstract. Imtiaz, K. E. Sweet root, bitter pill: liquorice-induced hyperaldosteronism. Ma, X. F. [Experimental and clinical studies on the treatment of pulmonary heart disease and pulmonary hypertension with Paeonia lactiflora]. Leem, K., Kim, H., Boo, Y., Lee, H. S., Kim, J. S., Yoo, Y. C., Ahn, H. J., Park, H. J., Seo, J. C., Kim, H. K., Jin, S. Y., Park, H. K., Chung, J. H., and Cho, J. J. Paeonia lactiflora (Chinese peony) and Paeonia brownii (California peony) relax smooth muscle tissue with a particular affinity for the female reproductive tract. Horm.Res 1999;52(5):253-255. J Ethnopharmacol 2002;81:101-4.. View abstract. Liquorice-induced rise in blood pressure: a linear dose-response relationship. Case 30-2020: A 54-Year-Old Man with Sudden Cardiac Arrest. View abstract. 2012;18(4):534-543. View abstract. View abstract. View abstract. Chen LC, Chou MH, Lin MF, Yang LL. Zhongguo Zhong.Xi.Yi Jie.He.Za Zhi 2008;28(12):1090-1092. Ha Y, Wang T, Li J, et al. No negative side effects. Saw palmetto. A., Lee, S. H., and Lee, S. M. Protective mechanism of glycyrrhizin on acute liver injury induced by carbon tetrachloride in mice. Migraine is a type of headache. Zhongguo Zhong.Xi.Yi Jie.He.Za Zhi 2008;28(12):1121-1123. View abstract. Chin Med J (Engl.) ""- . Taking licorice along with "water pills" might make potassium levels drop too low. Guo TL, Zhou XW. Licorice can be used orally with Peony to treat women with Polycystic Ovary Syndrom to increase fertility; it can also treat patients with abnormal Prolactin, muscle spasms, or to reduce the pain of cancer. Aldosterone is a hormone that causes your body to retain salt (sodium) and lose potassium. 2020. Effect of glycyrrhizin on the activity of CYP3A enzyme in humans. View abstract. Mamgain RK, Gupta M, Mamgain P, et al. (Tokyo) 2008;54(3):244-249. View abstract. Yorgun, H., Aksoy, H., Sendur, M. A., Ates, A. H., Kaya, E. B., Aytemir, K., and Oto, A. Brugada syndrome with aborted sudden cardiac death related to liquorice-induced hypokalemia. View abstract. Read more. Purnak, T., Ozaslan, E., Beyazit, Y., and Haznedaroglu, I. C. Upper gastrointestinal bleeding in a patient with defective hemostasis successfully treated with ankaferd blood stopper. B. Licorice-associated reversible cerebral vasoconstriction with PRES. We describe a patient who suffered life-threatening hypokalemic paralysis caused by consumption of licorice in the form of a tea sweetener superimposed on long . Clin Neurol Neurosurg 2003;105:286-7.. View abstract. 83rd Annual Meeting of the Endocrine Society, June 20-23 2001;abstract P1-573. Hawrelak, J. 5-10-2004;208(1):89-94. Licorice extract inhibits the production of tyrosinase, in turn inhibiting the production of dark spots. Some medications are changed and broken down by the liver. In an ovarietctomized model, oral administration of a combination of white peony and licorice increased DHEA and serum estrogen concentration. View abstract. Let's take a look at the forms, uses, and side effects of . Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents. Okubo T, Nagai F, Seto T, et al. View abstract. Arch Pharm Res 2002;25(3):293-299. J Hepatol 1994;21:601-9. Contact Dermatitis 1989; 20:152-3.. View abstract. The biological compound pesticide is manufactured from the raw materials of Ailanthus altissima Swingle, Cyrtomium fortunei, geranium wilfordii, fructus forsythiae, Scutellaria baicalensis, gallnut, areca-nut, coconut shell, radix sophorae . View abstract. View abstract. Drugs & Vitamins . Gatica-Ortega ME, Pastor-Nieto MA. Fitoterapia 2006;77(7-8):613-614. Radix Paeoniae Alba increases serum estrogen level and up-regulates estrogen receptor expression in uterus and vagina of immature/ovariectomized mice. J Pharmacobiodyn 1984;7:304-11. Acute myopathy associated with chronic licorice ingestion: reversible loss of myoadenylate deaminase activity. J Altern Complement Med 2010;16(10):1065-1071. View abstract. 2003;23(8):593-595. View abstract. View abstract. View abstract. Phytother Res 1988;2(3):140-145. Antiviral Res 1987;7(2):99-107. Hyodo T, Taira T, Kumakura M, et al. Antimicrobial isoflavanoids and related substances from Glycyrrhiza glabra L. var. Effects of glycyrrhizin on the pharmacokinetics of nobiletin in rats and its potential mechanism. Fitoterapia 2004;75:45-9.. View abstract. Red Peony Root (Paeniae Rubra Radix) 8 g Myrrh (Myrrha) . View abstract. Mol Cell Endocrinol. Francini-Pesenti F, Puato M, Piccoli A, Brocadello F. Liquorice-induced hypokalaemia and water retention in the absence of hypertension. It is often used together with peony, which can significantly enhance . Petramfar P, Hajari F, Yousefi G, Azadi S, Hamedi A. Efficacy of oral administration of licorice as an adjunct therapy on improving the symptoms of patients with Parkinson's disease, A randomized double blinded clinical trial. View abstract. Also for White Peony, the plant that is used in traditional . 1994;14:207-9, 195. . Licorice is Sita (cold) in nature, Guru (heavy) to digest, and Madhura (sweet) in . Low doses of liquorice can induce hypertension encephalopathy. [Treatment of chronic hepatitis B. 44 ($0.09/Count) NEW PACKAGING White Peony Root Bai Shao 4oz 38. . View abstract. Effect of glycyrrhizin on viral replication and quasispecies in patients with type C chronic hepatitis. Previous studies have estimated that a dose of 1 to 5 grams (g) of licorice root daily is safe for most adults. Hyodo T, Taira T, Kumakura M, et al. Anesth Analg. Nephrologie 1993;14(4):177-181. Clinical application of compound Glycyrrhizin tablets in the treatment of patients with Simplex Henoch-Schonlein Purpura and its effect on immune function. A randomized, crossover comparison of herbal medicine and bromocriptine against risperidone-induced hyperprolactinemia in patients with schizophrenia. View abstract. Lin SH, Yang SS, Chau T, Halperin ML. View abstract. View abstract. Nabeshima, S., Kashiwagi, K., Ajisaka, K., Masui, S., Takeoka, H., Ikematsu, H., and Kashiwagi, S. A randomized, controlled trial comparing traditional herbal medicine and neuraminidase inhibitors in the treatment of seasonal influenza. Dai DW, Singh I, Hershman JM. A randomized, double-blind comparison of licorice versus sugar-water gargle for prevention of postoperative sore throat and postextubation coughing. View abstract. Combined Lifestyle and Herbal Medicine in Overweight Women with Polycystic Ovary Syndrome (PCOS): A Randomized Controlled Trial. View abstract. . View abstract. [Study on activating blood and eliminating stasis of total paeony glycoside(TPG)]. The U.S. Food and Drug . Licorice root and white poney is a common herbal formula for PCOS originating in traditional Chinese medicine. J Endocrinol Invest 1996;19:624-9. Erratum in: Clin Rheumatol. Medicinal uses of licorice through the millennia: the good and plenty of it. BMJ Case Rep. 2013 Sep 19;2013. van der Zwan A. Kang, J. H., Park, Y. H., Choi, S. W., Yang, E. K., and Lee, W. J. Resveratrol derivatives potently induce apoptosis in human promyelocytic leukemia cells. Clin Pharmacol Ther 1996;59:62-71. View abstract. Additional reporting by Meghan De Maria. Clin Neurol Neurosurg 1993;95(1):35-37. Wen Y, Tang Y, Li M, Lai Y. J Med Liban 2012;60(2):117-119. Zhang XH, Lowe D, Giles P, et al. Yoshida S, Takayama Y. Licorice-induced hypokalemia as a treatable cause of dropped head syndrome. View abstract. Paeonia lactiflora : Peony is another popular anti-androgenic herb. Zhonghua Yi Xue Za Zhi 1983;63:477-81. Taking peony along with estrogen might increase the effects and side effects from estrogen. Gulf J Oncolog 2021;1(37):42-47. Lorenzin, F., Degen, C., Milani, A., Siciliano, M., and Rossi, L. [Pseudo-hyperaldosteronism caused by licorice. View abstract. [Effect of fu-zheng qu-xie on gastric disease infected with Campylobacter pyloridis]. Oh, G. S., Pae, H. O., Oh, H., Hong, S. G., Kim, I. K., Chai, K. Y., Yun, Y. G., Kwon, T. O., and Chung, H. T. In vitro anti-proliferative effect of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose on human hepatocellular carcinoma cell line, SK-HEP-1 cells. White peony ( bai shao in Chinese) is root without any bark, while red peony . [Paeonia Lactiflora injection in treating chronic cor pulmonale with pulmonary hypertension]. A specific type of peony product, total glucosides of peony (TGP), has most often been used by adults in doses of 600 mg by mouth three times daily for up to 24 weeks. View abstract. Stormer FC, Reistad R, Alexander J. Glycyrrhizic acid in liquorice - evaluation of health hazard. But I didn't take it long enough to see any change. It's not suggested to take St. John's wort if you take blood thinners. What are the side-effects of taking liquorice? 2020;383(13):1263-1275. Steroids 2004;69(11-12):763-766. View abstract. Hypertension and the cortisol-cortisone shuttle. J Hum Hypertens 1995;9:345-8. Lancet 2003;361:2045-6.. View abstract. Taking peony along with medications that also slow blood clotting might increase the risk of bruising and bleeding. Some of these health benefits have also . J Neuroophthalmol. To learn more about how herbs are used to treat infertility, see this article. Phytotherapy Research 1997;11:207-210. van Gelderen, C. E., Bijlsma, J. View abstract. Brayley J, Jones J. Life-threatening hypokalemia associated with excessive licorice ingestion (letter). View abstract. Chien, C. F., Wu, Y. T., and Tsai, T. H. Biological analysis of herbal medicines used for the treatment of liver diseases. View abstract. Licorice (Glycyrrhizae Radix) 15 g: NR: Zhao (2016) [36] . Licorice that has the active ingredient of glycyrrhiza can have serious side effects. View abstract. Intern Med 2007;46:575-8. Yang HO, Ko WK, Kim JY, Ro HS. 2020 Dec;58(1):352-356. View abstract. Cureus 2020;12(11):e11656. Licorice might increase blood pressure. 6. Licorice-induced hypermineralocorticoidism. Grapefruit juice and its flavonoids inhibit 11 beta-hydroxysteroid dehydrogenase. The effects of licorice containing diphenhydramine solution on recurrent aphthous stomatitis: A double-blind, randomized clinical trial. 1991;78(1-2):1-6. Note: Results may vary from person to person, depending on the skin type. Visavadiya, N. P. and Narasimhacharya, A. V. Hypocholesterolaemic and antioxidant effects of Glycyrrhiza glabra (Linn) in rats. Nephol Dial Transplant 1999;14:218-20. Balakrishnan, V., Pillai, M. V., Raveendran, P. M., and Nair, C. S. Deglycyrrhizinated liquorice in the treatment of chronic duodenal ulcer. Ito, M., Sato, A., Hirabayashi, K., Tanabe, F., Shigeta, S., Baba, M., De Clercq, E., Nakashima, H., and Yamamoto, N. Mechanism of inhibitory effect of glycyrrhizin on replication of human immunodeficiency virus (HIV). Clinical and immunological consequences of total glucosides of paeony treatment in Sjgren's syndrome: A randomized controlled pilot trial. Although white peony is generally considered safe for most people, drinking large amounts might have some negative consequences. Rev Med Brux 2008;29(5):490-493. View abstract. A., van der Ven, P. F., Martin, M., Sherman, J., and Haley, J. 2014 Jun;23(3):189-92. N Engl J Med 1991;325:1223-7. Z Gastroenterol 2001;39(7):511-7. Lozano, P., Flores, D., Martinez, S., Artigues, I., Rimbau, E. M., and Gomez, F. Upper limb ischemia induced by chronic licorice ingestion. J Altern Complement Med 2000;6:557-9. View abstract. View abstract. Side-effects of low-potassium levels can include lethargy and abnormal heart rhythms. View abstract. Int Immunopharmacol 2012;14(1):27-31. View abstract. Yamashiki, M., Nishimura, A., Suzuki, H., Sakaguchi, S., and Kosaka, Y. Licorice is an herb that grows in parts of Europe and Asia. View abstract. N Engl J Med 1968;278(25):1381-1383. View abstract. Oh, G. S., Pae, H. O., Choi, B. M., Lee, H. S., Kim, I. K., Yun, Y. G., Kim, J. D., and Chung, H. T. Penta-O-galloyl-beta-D-glucose inhibits phorbol myristate acetate-induced interleukin-8 [correction of intereukin-8] gene expression in human monocytic U937 cells through its inactivation of nuclear factor-kappaB. Cureus 2021;13(7):e16454. mentioned adverse effects and recurrence rates. View abstract. Costa, A., Moises, T. A., Cordero, T., Alves, C. R., and Marmirori, J. View abstract. Exp.Mol.Med 12-31-2003;35(6):467-474. View abstract. All rights reserved. Coloclyster of Red Peony Root Granules Alleviates Moderately Severe Acute Pancreatitis: A Double-Blinded, Placebo-Controlled, Randomized Clinical Trial. Madisch A, Melderis H, Mayr G, et al. View abstract. Yu IC, Tsai YF, Fang JT, Yeh MM, Fang JY, Liu CY. Hinoshita F, Ogura Y, Suzuki Y, et al. View abstract. Neth J Med 2005;63:149-50. View abstract. Chewing tobacco flavored with Licorice may cause serious side effects such as high blood pressure. Growth-inhibiting, bactericidal, and urease inhibitory effects of Paeonia lactiflora root constituents and related compounds on antibiotic-susceptible and -resistant strains of Helicobacter pylori. We could use compounds in these foods to . Kimura Y, Okuda H, Okuda T, and et al. A botanical dietary supplement from white peony and licorice attenuates nonalcoholic fatty liver disease by modulating microbiota and reducing inflammation . BMJ Case Rep 2012;2012. Paeoniflorin's. Since the content of glycyrrhizin is either decreased or removed from the DGL licorice supplement, its positive effects on PCOS may also be reduced. J Tradit.Chin Med 2010;30(1):47-50. Blood Press. View abstract. View abstract. [Comparison of pre- and post-treatmental hepatohistology with heavy dosage of Paeonia rubra on chronic active hepatitis caused liver fibrosis]. Int Immunopharmacol. Ann Mtg Digestive Disease Week 1999 May. Can J Cardiol 2009;25(10):e357-e358. View abstract. Yuan, H. N., Wang, C. Y., Sze, C. W., Tong, Y., Tan, Q. R., Feng, X. J., Liu, R. M., Zhang, J. Too much black licorice, the federal agency says, can lead to "abnormal heart rhythms, as well as high blood pressure, edema (swelling), lethargy, and congestive heart failure." . Monitor your blood pressure closely. 30. View abstract. Bannister, B., Ginsburg, R., and Shneerson, J. Cardiac arrest due to liquoriceinduced hypokalaemia. Mitscher, L. A., Park, Y. H., Clark, D., and Beal, J. L. Antimicrobial agents from higher plants. View abstract. B., and Zhang, Z. J. Asia Pac.J Clin Nutr 2008;17(1):17-22. Cisplatin is used to treat cancer. van Uum SH. View abstract. But, she survived . Wang H, Dong L, Qu F, et al. Front Psychiatry 2020;11:605949. Other conditions. Ito A, Hayashi N, Katayama K, and et al. This might increase the effects and side effects of methotrexate. 2000;20(1):38-41. Licorice can decrease potassium levels. Eur J Drug Metab Pharmacokinet. J Nutr 2001;131:1471-8. View abstract. Astragalus may be safe when used orally and appropriately. J Dermatolog Treat 2003;14(3):153-157. A systemic review and meta-analysis of the clinical efficacy and safety of total glucosides of peony combined with methotrexate in rheumatoid arthritis. View abstract. Guo, D., Ye, G., and Guo, H. A new phenolic glycoside from Paeonia lactiflora. The dogs treated with the herbal mixture saw a 37.5 percent improvement . (Glycyrrhiza glabra), it performs better, especially for relaxing muscles, reducing painful menstruation, as well as lowering serum and free testosterone levels in women with PCOS. Li J, Fan X, Wang Q. Hypertensive crisis with 2 target organ impairment induced by glycyrrhizin: a case report. Peony might change how quickly the liver breaks down these medications. PCOS; Fertility; 25 - 45; Menopause; 45 - 60; Pregnancy View abstract. A., Ziaee, A., and Samimi, R. The efficacy of licorice root extract in decreasing transaminase activities in non-alcoholic fatty liver disease: a randomized controlled clinical trial. Jia, Y. Strandberg TE, Andersson S, Jarvenpaa AL, et al. Gut 1973;14(9):711-715. Fermented milk containing Lactobacillus paracasei and Glycyrrhiza glabra has a beneficial effect in patients with Helicobacter pylori infection: a randomized, double-blind, placebo-controlled study. Kumada T, et al. The combination alters the Luteinising Hormone vs Follicle Stimulating Hormone ratio that is abnormal in PCOS. N Engl J Med 1990;322:850. Zhongguo Zhong.Xi.Yi Jie.He.Za Zhi 2008;28(4):358-360. Bruynzeel DP. Br J Clin Pract 1972;26(12):563-566. J Clin Psychopharmacol 2008;28(3):264-370. Low potassium levels can increase the side effects of digoxin. 1. View abstract. Deglycyrrhizinated liquorice in aphthous ulcers. View abstract. Int Endod.J 2011;44(1):51-58. In general, the safety and effectiveness of alternative medicines have not been scientifically proven and remain largely unknown. View abstract. Dying for a cup of tea. View abstract. Taking licorice with paclitaxel might decrease the effects of paclitaxel. All rights reserved. Z Kardiol 1991;80(6):389-391. A dual investigation of the effect of dietary supplementation with licorice flavonoid oil on anthropometric and biochemical markers or health and adiposity. Kormann R, Languille E, Amiot HM, Hertig A. Case Rep Emerg Med. 2013 Jun;22(2):173-8. Luper, S. A review of plants used in the treatment of liver disease: part two. Licorice consumption and serum testosterone in healthy man. Z. Luo, Y. G., Liu, Y. Q., and Hu, J. View abstract. View abstract. Liu X, Li X, Li X, et al. Hossain, M. S., Takimoto, H., Hamano, S., Yoshida, H., Ninomiya, T., Minamishima, Y., Kimura, G., and Nomoto, K. Protective effects of hochu-ekki-to, a Chinese traditional herbal medicine against murine cytomegalovirus infection. Journal of Clinical Therapeutics Medicine. 2004;24(12):1084-1086. 2004;4(3):377-386. 4-14-2001;145(15):744-747. Eur J Pharmacol 1981;72:219-25.. View abstract. View abstract. Iran J Pharm Res 2012;11(2):541-8. Gallacher SD, Tsokolas G, Dimitropoulos I. Liquorice-induced apparent mineralocorticoid excess presenting in the emergency department. Myopathies associated with red yeast rice and liquorice: spontaneous reports from the Italian Surveillance System of Natural Health Products. Int J Nurs Stud 2016;63:9-17. Licorice root extract is often used to relieve symptoms of indigestion, such as acid reflux, upset stomach, and heartburn. Licorice might decrease the effects of warfarin. Treatment of duodenal ulcer with glycyrrhizinic-acid-reduced liquorice. Effect of Japanese Angelica root and peony root on uterine contraction in the rabbit in situ. Licorice has anti-acid and relieves the tension of gastrointestinal smooth muscle. Chamberlain, J. J. and Abolnik, I. Johns, C. Glycyrrhizic acid toxicity caused by consumption of licorice candy cigars. Peony might slow blood clotting. Z., Zhang, Y. Cooper, H., Bhattacharya, B., Verma, V., McCulloch, A. J., Smellie, W. S., and Heald, A. H. Liquorice and soy sauce, a life-saving concoction in a patient with Addison's disease. 1991;4(2):166-173. Panduranga P, Al-Rawahi N. Licorice-induced severe hypokalemia with recurrent torsade de pointes. View abstract. J Clin Hypertens (Greenwich) 2016;18(2):159-60. View abstract. Ai, M., Yamaguchi, T., Odaka, T., Mitsuhashi, K., Shishido, T., Yan, J., Seza, A., and Saisho, H. Objective assessment of the antispasmodic effect of shakuyaku-kanzo-to (TJ-68), a Chinese herbal medicine, on the colonic wall by direct spraying during colonoscopy.